【摘要】 目的 调查老年精神分裂症(schizophrenia,SZ)患者睡眠障碍情况,并分析其影响因素。方法 回顾性分析2022年6月至2024年6月在我院进行诊治的121例老年SZ患者的临床资料,依据匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)将SZ患者分为睡眠障碍组66例(PSQI≥7分)和无睡眠障碍组55例(PSQI<7分)。比较两组患者相关基线资料、阳性及阴性症状量表(Positive And Negative Syndrome Scale,PANSS)评分及蒙哥马利抑郁量表(Montgomery-Asberg Depression Rating Scale,MADRS)总分,通过多因素分析老年SZ患者睡眠障碍的危险因素。结果 睡眠障碍组年龄、PANSS-P评分、PANSS-G评分、MADRS总分高于无睡眠障碍组(P<0.05)。经多因素Logistic回归分析证实,高龄、PANSS-P评分、PANSS-G评分、MADRS总分升高是老年SZ患者睡眠障碍的危险因素,均有P<0.05。结论 老年SZ患者易出现睡眠障碍,且高龄、PANSS-P评分、PANSS-G评分、MADRS总分均是老年SZ患者睡眠障碍的影响因素,临床上应引起足够重视。
关键词: 【关键词】老年;精神分裂症;睡眠障碍;影响因素
【Abstract】Objective To investigate the sleep disorder in elderly patients with schizophrenia (SZ) and analyze its influencing factors.Methods Clinical data of 121 elderly patients with SZ treated in our hospital from June 2022 to June 2024 were retrospectively analyzed according to the Pittsburgh sleep quality index (PSQI). SZ patients were divided into sleep disorder group 66 cases (PSQI≥7 points) and no sleep disorder group 55 cases (PSQI < 7 points). Relevant baseline data, Positive And Negative Syndrome Scale (PANSS) scores and Montgomery-Asberg Depression Rating Scale (MADRS) were compared between the two groups. The risk factors of sleep disorders in elderly patients with SZ were analyzed by multiple factors. Results Age, PANSS-P score, PANSS-G score and total MADRS score in sleep disorder group were higher than those in no sleep disorder group (P<0.05). Multivariate Logistic regression analysis confirmed that old age, PANSS-P score, PANSS-G score and MADRS total score were risk factors for sleep disorders in elderly patients with SZ, all with P<0.05. Conclusion Elderly SZ patients are prone to sleep disorders, and old age, PANSS-P score, PANSS-G score and MADRS total score are all influential factors of sleep disorders in elderly SZ patients, which should be paid sufficient attention to clinically.
Key words: 【Key words】 Old age; Schizophrenia; Sleep disorders; Influencing factor

ISSN:1673-2952
CN:43-1457/R
主管单位:中华人民共和国教育部
主办单位:中南大学
刊期:双月刊
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